Changelog¶
This page documents significant releases, new features, improvements, and bug fixes for the AIVA platform. Entries are listed in reverse chronological order.
For real-time update notifications, check the "What's New" announcements in the AIVA application.
2026-04-04¶
New Features
- Optional SNV/Indel calling: FASTQ uploads now allow disabling SNV/Indel downstream processing. When disabled, only BAM files and raw VCF are produced. Enabled by default.
- CNV calling: Optional copy number variation analysis, available as an add-on for FASTQ uploads. Results are annotated and loaded into AIVA for analysis.
- SV calling: Optional structural variant calling, available as an add-on for FASTQ uploads. Results are annotated and loaded into AIVA for analysis.
- VCF download link: Sample cards now show a VCF download link alongside BAM files for all pipeline-processed samples.
Improvements
- Haplotype phasing: Read phasing is now always enabled for germline and somatic paired pipelines, adding haplotype information to all variant calls.
- Compressed VCF output: Pipelines now output compressed VCF files, reducing storage costs.
2026-03-30¶
New Features
- Playbooks: Reusable, step-by-step AI analysis playbooks for standardized genomic workflows. Browse community-contributed playbooks in the marketplace, create your own, or fork and customize existing ones. See Playbooks.
- Pharmacogenomics (PGx) analysis: Automatically assign star alleles, predict metabolizer phenotypes, and generate CPIC drug recommendations for 88 pharmacogenes as part of the secondary analysis pipeline. See Pharmacogenomics.
- WES/WGS credit pricing: Credits are now charged per sample. WES costs 2 credits and WGS costs 3 credits.
Improvements
- Updated the Plus and Pro tier UI to display WES/WGS credit costs and storage slot counts (including BAMs).
Release Notes Format¶
Each release entry includes the following sections as applicable:
| Section | Description |
|---|---|
| New Features | Entirely new capabilities added to the platform. |
| Improvements | Enhancements to existing features, performance improvements, and UX refinements. |
| Bug Fixes | Corrections to issues reported by users or discovered during testing. |
| Breaking Changes | Changes that may require user action, such as API changes, deprecated features, or modified workflows. |
| Security | Security patches and vulnerability fixes. |
| Deprecations | Features that are planned for removal in a future release. |
Staying Updated¶
- In-app announcements: The "What's New" notification in the AIVA navigation bar highlights the most important changes.
- This changelog: Comprehensive release notes for all updates.
- API changes: Breaking API changes are communicated through this changelog. See API Reference.